tau-441 (P301S) protein (His tag)
Aperçu rapide pour tau-441 (P301S) protein (His tag) (ABIN7482545)
Antigène
Type de proteíne
Origine
Source
Pureté
Classe de qualité
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Attributs du protein
- P301S
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Purification/Conjugué
- His tag
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Fonction
- Human Tau-441 / 2N4R (P301S) Protein, His Tag (MALS verified)
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Séquence
- Met 1 - Leu 441
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Attributs du produit
- Human Tau-441 (P301S), His Tag is expressed from E.coli cells. It contains AA Met 1 - Leu 441 (Accession # P10636-8 (P301S).
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niveau d'endotoxine
- 1.0 EU per μg
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Commentaires
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This protein carries a polyhistidine tag at the N-terminus. (10xHis) The protein has a calculated MW of 47.7 kDa. The protein migrates as 66 kDa under reducing (R) condition (SDS-PAGE).
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Stock
- -20 °C
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Stockage commentaire
- -20°C
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- tau-441
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Sujet
- Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies.
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Poids moléculaire
- 47.7 kDa
Antigène
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