TNFSF15 Protéine

N° du produit ABIN7488820

Cette protéine Recombinant TNFSF15 est produite dans HEK-293 Cells.

Aperçu rapide pour TNFSF15 Protéine (ABIN7488820)

Antigène: TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Pureté: 90 %

Détail du produit

Fonction: Human TL1A / TNFSF15 Protein, His Tag

Séquence: Met 1 - Leu 192

Attributs du produit: Human TL1A Protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Met 1 - Leu 192 (Accession # O95150-2).

niveau d'endotoxine: 1.0 EU per μg

Information d'application

Commentaires:

This protein carries a polyhistidine tag at the N-terminus. () The protein has a calculated MW of 23.7 kDa. The protein migrates as 30 kDa and 31-33 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Stock: -20 °C

Stockage commentaire: -20°C

Détail du antigène

Antigène: TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))

Autre désignation: TL1A

Sujet: TNF-like cytokine 1A (TL1A) and its receptors, death receptor 3 (DR3) and decoy receptor 3 (DcR3) are members of the TNF and TNF receptor superfamilies of proteins, respectively. Binding of APC-derived TL1A to lymphocytic DR3 provides co-stimulatory signals for activated lymphocytes. DR3 signaling affects not only the proliferative activity of and cytokine production by effector lymphocytes, but also critically influences the development and suppressive function of regulatory T-cells. Whereas, DcR3 restricts the function of the TL1A/DR3 complex: attenuating T-cell activation and downregulating the secretion of pro-inflammatory cytokines. Together with DR3 and DcR3, TL1A constitutes a cytokine system that actively interferes with the regulation of immune responses.

Poids moléculaire: 23.7 kDa

Pathways: Positive Regulation of Endopeptidase Activity, Autophagy