Rubella Virus E2 protein (His tag)

N° du produit ABIN7482619

Protéine Recombinant exprimée dans HEK-293 Cells.

Aperçu rapide pour Rubella Virus E2 protein (His tag) (ABIN7482619)

Antigène: Rubella Virus E2

Type de proteíne: Recombinant

Origine: Rubella Virus (RuV)

Source: HEK-293 Cells

Pureté: 90 %

Détail du produit

Purification/Conjugué: His tag

Fonction: Rubella virus Glycoprotein E2 (strain M33) (RUBV), His Tag (HPLC-verified)

Séquence: Gly 301- Ala 532

Attributs du produit: Rubella virus Glycoprotein E2 (strain M33) (RUBV), His Tag is expressed from human 293 cells (HEK293). It contains AA Gly 301- Ala 532 (Accession # P08563).

niveau d'endotoxine: 1.0 EU per μg

Information d'application

Commentaires:

This protein carries a polyhistidine tag at the C-terminus. (10xHis) The protein has a calculated MW of 26.7 kDa. The protein migrates as 45-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Stock: -20 °C

Stockage commentaire: -20°C

Détail du antigène

Antigène: Rubella Virus E2

Autre désignation: Rubella virus Glycoprotein E2

Classe de substances: Viral Protein

Sujet: Herpesvirus infections are widely spread throughout the world population. Herpes simplex virus (HSV) belongs to the α-herpesvirus subfamily. There are two main types of HSV, HSV-1 and HSV-2, which infect humans. HSV-2 mainly causes genital lesions, whereas HSV-1 is involved in both oral and genital infections. In epithelial cells, the heterodimer gE/gI is required for the cell-to-cell spread of the virus, by sorting nascent virions to cell junctions. Once the virus reaches the cell junctions, virus particles can spread to adjacent cells extremely rapidly through interactions with cellular receptors that accumulate at these junctions. Implicated in basolateral spread in polarized cells. In neuronal cells, gE/gI is essential for the anterograde spread of the infection throughout the host nervous system.

Poids moléculaire: 26.7 kDa