Claudin 4 Protein-VLP (CLDN4) (AA 1-209)

N° du produit ABIN7504302

Cette protéine VLP Claudin 4 est produite dans HEK-293 Cells.

Aperçu rapide pour Claudin 4 Protein-VLP (CLDN4) (AA 1-209) (ABIN7504302)

Antigène: Claudin 4 (CLDN4)

Type de proteíne: VLP

Origine: Humain

Source: HEK-293 Cells

Pureté: > 95 % as determined by HPLC

Détail du produit

Attributs du protein: AA 1-209

Fonction: Human Claudin 4 Protein-VLP

Séquence: Met1-Val209

Attributs du produit: Recombinant Human Claudin 4 Protein-VLP is expressed from HEK293.It contains Met1-Val209.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied as 0.22μm filtered solution in PBS, 300 mM L-Arginine ( pH 7.4). Notice: If you need it for immunization, Do Not use any adjuvant.

Stock: -80 °C

Stockage commentaire: Valid for 12 months from date of receipt when stored at -80°C.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: Claudin 4 (CLDN4)

Autre désignation: Claudin 4

Sujet: Claudin-4 (CLDN4) is a key component of tight junctions (TJs) in epithelial cells. CLDN4 is overexpressed in many epithelial malignancies and correlates with cancer progression. Changes in CLDN4 expression have been associated with epigenetic factors (such as hypomethylation of promoter DNA), inflammation associated with infection and cytokines, and growth factor signaling. CLDN4 helps to maintain the tumor microenvironment by forming TJs and acts as a barrier to the entry of anticancer drugs into tumors.

Poids moléculaire: 23.31 kDa.

UniProt: O14493

Pathways: Hepatitis C