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IL29 Protein (AA 1-200)

Cette protéine Recombinant IL29 est exprimée dans HEK-293 Cells.
N° du produit ABIN7505594

Aperçu rapide pour IL29 Protein (AA 1-200) (ABIN7505594)

Antigène

Voir toutes IL29 Protéines
IL29 (Interleukin 29 (IL29))

Type de proteíne

Recombinant

Origine

  • 15
  • 1
  • 1
Humain

Source

  • 10
  • 4
  • 2
  • 1
HEK-293 Cells

Pureté

> 95 % as determined by reducing SDS-PAGE.
  • Attributs du protein

    AA 1-200

    Séquence

    Met1-Thr200

    Attributs du produit

    A DNA sequence encoding the Human IL-29 Protein(Q8IU54)(1-200)was expressed with a polyhistidine tag at the N-terminus.

    niveau d'endotoxine

    <1.0 EU per μg of the protein as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from sterile PBS, pH 7.4., 5 % trehalose, 5 % mannitol, 0.01 % tween-80.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

    Stock

    4 °C,-20 °C,-80 °C

    Stockage commentaire

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    Date de péremption

    12 months
  • Antigène

    IL29 (Interleukin 29 (IL29))

    Autre désignation

    IL-29

    Sujet

    Abbreviation: IL-29

    Target Synonym: Interferon lambda-1,IFN-lambda-1,ytokine Zcyto21,Interleukin-29,IL29,IFNL1,ZCYTO21

    Background: Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.

    Poids moléculaire

    Calculated MW: 22 kDa

    Observed MW: 28-35 kDa

    UniProt

    Q8IU54
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