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CCL1 Protéine

CCL1 Origine: Humain Hôte: Yeast (Pichia pastoris) Recombinant > 95 % by SDS-PAGE.
N° du produit ABIN7535999
  • Antigène Voir toutes CCL1 Protéines
    CCL1 (Chemokine (C-C Motif) Ligand 1 (CCL1))
    Type de proteíne
    Recombinant
    Origine
    • 12
    • 4
    • 1
    • 1
    Humain
    Source
    • 8
    • 5
    • 2
    • 2
    • 1
    Yeast (Pichia pastoris)
    Fonction
    Recombinant Human CCL1/I-309 Protein
    Séquence
    KSMQVPFSRC CFSFAEQEIP LRAILCYRNT SSICSNEGLI FKLKRGKEAC ALDTVGWVQR HRKMLRHCPS KRK
    Specificité
    Lys24-Lys96
    Pureté
    > 95 % by SDS-PAGE.
    Stérilité
    0.22 μm filtered
    niveau d'endotoxine
    <0.1EU/μg
    Top Product
    Discover our top product CCL1 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    Buffer
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
  • Antigène
    CCL1 (Chemokine (C-C Motif) Ligand 1 (CCL1))
    Autre désignation
    CCL1/I-309 (CCL1 Produits)
    Synonymes
    I-309 Protein, P500 Protein, SCYA1 Protein, SISe Protein, TCA3 Protein, BF534335 Protein, Scya1 Protein, Tca-3 Protein, CCLi6 Protein, chemokine Protein, C-C motif chemokine ligand 1 Protein, chemokine (C-C motif) ligand 1 Protein, CCL1 Protein, Ccl1 Protein
    Sujet

    Description: CCL1 or chemokine (C-C motif) ligand 1, also known as I-309 or TCA-3, is a member of the chemokine (C-C motif) ligand family. The C-C chemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands (CCL)-1 to 28. I-309/CCL1/TCA-3 interacts with the G protein-linked transmembrane chemokine receptors CCR8 and induces biochemical events that may result in the control of chemotaxis, proliferation, apoptosis and adhesion. It has been demonstrated that I-309/CCL1/TCA-3 displays chemotactic activity for monocytes and other cell types such as NK cells and dendritic cells, but not for neutrophils. Furthermore, as the only known physiological ligand for CCR8, I-309/CCL1/TCA-3 was identified as a potent inhibitor of HIV-1 envelope-mediated cell-cell fusion and virus infection. I-309/CCL1/TCA-3 induces significant levels of LTC4 from elicited eosinophils.

    Name: CCL1,I-309,P500,SCYA1,SISe,TCA3

    ID gène
    6346
    UniProt
    P22362
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