PDGF-AA Homodimer Protéine
Aperçu rapide pour PDGF-AA Homodimer Protéine (ABIN7536482)
Antigène
Type de proteíne
Origine
Source
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Fonction
- Recombinant Human PDGF-AA Protein
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Séquence
- SIEEAVPAVC KTRTVIYEIP RSQVDPTSAN FLIWPPCVEV KRCTGCCNTS SVKCQPSRVH HRSVKVAKVE YVRKKPKLKE VQVRLEEHLE CACATTSLNP DYREEDTGRP RESGKKRKRK RLKPT
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Specificité
- Ser87-Thr211
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Stérilité
- 0.22 μm filtered
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niveau d'endotoxine
- 600.1EU/μg
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
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Concentration
- 0.17 mg/mL
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Buffer
- Lyophilized from a 0.22 μm filtered solution of 20 mM NaAc, pH 4.5
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- PDGF-AA Homodimer
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Autre désignation
- PDGF-AA
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Sujet
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Description: Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell proliferation, angiogenesis and metastasis. The human platelet-derived growth factor A chain gene (PDGFA) on chromosome 7p22 encodes an important mitogen. Within PDGFA lies a complex minisatellite structure that results in partial duplications of exon 4 and the IVS4 splice donor site.
Name: PDGF1, PDGF-A
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ID gène
- 5154
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UniProt
- P04085
Antigène
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