SCYL2 Protein (AA 1-930) (His tag)

N° du produit ABIN7564555

Cette protéine Recombinant SCYL2 est produite dans HEK-293 Cells.

Aperçu rapide pour SCYL2 Protein (AA 1-930) (His tag) (ABIN7564555)

Antigène: SCYL2 (SCY1-Like 2 (SCYL2))

Type de proteíne: Recombinant

Origine: Souris

Source: HEK-293 Cells

Pureté: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Classe de qualité: custom-made

Détail du produit

Attributs du protein: AA 1-930

Purification/Conjugué: Cette SCYL2 protéine est marqué à la His tag.

Fonction: Predefined custom protein recombinant Scyl2 Protein expressed in mammalian cells.

Séquence: MESMLNKLKS TVTKVTADVT SAVMGNPVTR EFDVGRHIAS GGNGLAWKIF NGTKKSTKQE VAVFVFDKKL IDKYQKFEKD QIIDSLKRGV QQLTRLRHPR LLTVQHPLEE SRDCLAFCTE PVFASLANVL GNWENLPSSI SPDIKDYKLY DVETKYGLLQ VSEGLSFLHS SVKMVHGNVT PENVILNKSG AWKIMGFDFC VSSSNPSEQE PKFPCKEWDP NLPSLCLPNP EYLAPEYILS VSCETASDMY SLGAVMYAVF NQGRPIFEVN KQDIYKSFSR QLDQLSRLGS SSLTSIPEEV REHVKLLLNV TPTVRPDADQ MTKIPFFDDV GAVTLQYFDT LFQRDNLQKS QFFKGLPKVL PKLPKRVIVQ RILPCLTSEF VNPDMVPFVL PNVLLIAEEC TKEEYIKLIL PELGPVFKQQ EPIQILLIFL QKMDLLLTKT PPDEIKNSVL PMVYRALEAP SIQIQELCLN IIPTFANLID YPSMKNALIP RIKNACLQTS SLAVRVNSLV CLGKILEYLD KWFVLDDILP FLQQIPSKEP AVLMGILGIY KCTFTHKKLG ITKEQLAGKV LPHLIPLSIE NNLNLNQFSS FIAVIKEMLS RLESEHRTKL EQLHVMQEQQ RSLDIGNQMS TSEETKVAHS GSQQIDKVFN NIGADLLSGS ESENREDGMQ GKQKRGSLTL EEKQKLAKEQ EQAQKLKSQQ PLKPQVHTPI APIKQTKDLT DTLMENMSSL TSLSVSTPKI SASSTFTPVP STGLGMMFST PIDNTKRNLT NGLNANMGFQ TSGFSMPVNP NQNFFSGTGT AGVTTMSLGA PPTMSNFSPL TIPPASVKQP QQRPTDMSAL NNLFGPQKPK VSMNQLSQQK PNQWLNQFAP PQGSPVMGSA AMGTQGNVMG QAAFGMQGNP FFNPQNFAQP PPTTMTSSSS ASNDLKDLFG Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificité: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Attributs du produit: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Information d'application

Indications d'application: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -80 °C

Stockage commentaire: Store at -80°C.

Date de péremption: 12 months

Détail du antigène

Antigène: SCYL2 (SCY1-Like 2 (SCYL2))

Autre désignation: Scyl2

Sujet: SCY1-like protein 2 (Coated vesicle-associated kinase of 104 kDa),FUNCTION: Component of the AP2-containing clathrin coat that may regulate clathrin-dependent trafficking at plasma membrane, TGN and endosomal system. A possible serine/threonine-protein kinase toward the beta2-subunit of the plasma membrane adapter complex AP2 and other proteins in presence of poly-L-lysine has not been confirmed (By similarity). By regulating the expression of excitatory receptors at synapses, plays an essential role in neuronal function and signaling and in brain development (PubMed:26203146). {ECO:0000250|UniProtKB:Q6P3W7, ECO:0000269|PubMed:26203146}.

Poids moléculaire: 103.3 kDa

UniProt: Q8CFE4

AlphaFold: Q8CFE4