alpha-Latrotoxin (Active) Protéine

N° du produit ABIN7887287

Cette protéine Native alpha-Latrotoxin est exprimée dans Latrodectus tredecimguttatus (Mediterranean black widow spider).

Aperçu rapide pour alpha-Latrotoxin (Active) Protéine (ABIN7887287)

Antigène: alpha-Latrotoxin

Type de proteíne: Native

Activité biologique: Active

Origine: Latrodectus tredecimguttatus

Source: Latrodectus tredecimguttatus (Mediterranean black widow spider)

Pureté: ≥97 %

Détail du produit

Fonction: α-Latrotoxin

Specificité: Toxin target: Neurexin-1, ADGRL1 (latrophilin-1/CIRL), and tyrosine-protein phosphatase S (PTPRS) receptors

Biological Activity Comment: α-Latrotoxin induces exhaustive neurotransmitter release from nerve terminals1. Indirectly activates the ERK MAP kinase pathway.

Information d'application

Indications d'application: Antigen Preadsorption Control: 150 pM - 1 nM

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the vial at 10,000 x g for 5 minutes before opening to ensure all material is collected at the bottom. The lyophilized product may be difficult to visualize. Carefully add the solvent directly to the vial interior. Dissolve the material by gently tapping, tilting, or rolling the vial. Avoid vigorous shaking or vortexing Reconstitute in high-quality pure water or a conventional buffer (e.g., 25 mM Tris-HCl pH 8.0, 150 mM NaCl, 0.1 mM CaCl₂, and 0.2 mM MgCl₂). Avoid multiple freeze-thaw cycles and maintain optimal biological activity.

Buffer: Lyophilized from 20 mM KPO4 buffer, pH 6.8.

Conseil sur la manipulation: Centrifuge the vial at 10,000 x g for 5 minutes before opening to ensure all material is collected at the bottom. protect from moisture

Stock: -20 °C

Stockage commentaire: The product is shipped as a lyophilized powder at room temperature. Upon receipt, store at -20°C and protect from moisture.

Détail du antigène

Antigène: alpha-Latrotoxin

Sujet: A potent inducer of massive neurotransmitter release via presynaptic neurexin and latrophilin receptors

Poids moléculaire: 130 kDa

UniProt: P23631

Numéro CAS: 65988-34-3