MitTx Toxin (Active) Protéine

N° du produit ABIN7887288

Protéine Native MitTx Toxin exprimée dans Micrurus tener tener (Texas coral snake).

Aperçu rapide pour MitTx Toxin (Active) Protéine (ABIN7887288)

Antigène: MitTx Toxin

Type de proteíne: Native

Activité biologique: Active

Origine: Micrurus tener tener

Source: Micrurus tener tener (Texas coral snake)

Pureté: ≥98 % (HPLC)

Détail du produit

Fonction: MitTx Toxin

Séquence: MitTx-α subunit:
QIRPAFCYED PPFFQKCGAF VDSYYFNRSR ITCVHFFYGQ CDVNQNHFTT MSECNRVCHG
MitTx-β subunit:
NLNQFRLMIK CTNDRVWADF VDYGCYCVAR DSNTPVDDLD RCCQAQKQCY DEAVKVHGCK PLVMFYSFEC RYLASDLDCS GNNTKCRNFV CNCDRTATLC ILTATYNRNN HKIDPSRCQ

Specificité: Toxin target: ASIC1-containing acid-sensing ion channels (ASICs) 

Biological Activity Comment: MitTx toxin activates ASIC1-containing channels1,2.

Information d'application

Indications d'application: Antigen Preadsorption Control: 20 nM

Commentaires:

Electrophysiology

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the vial at 10,000 x g for 5 minutes before opening to ensure all material is collected at the bottom. The lyophilized product may be difficult to visualize. Add solvent directly to the centrifuged vial and dissolve by gently tapping, tilting, or rolling the vial. Avoid vigorous vortexing, a brief, light vortex of 1-2 seconds is acceptable if necessary. The product is readily soluble in high-quality pure water at micromolar to millimolar concentrations (typically 100 μM to 1  mM). For long-term storage in solution, we recommend preparing a stock solution by dissolving the product in double-distilled water (ddH2O) at a concentration between 100-1000x the final working concentration. Divide the stock solution into small, single-use aliquots and store at -20 °C. Before use, thaw the relevant vial(s) and dilute to the desired working concentration in your working buffer. Centrifuge all product preparations before use. It is recommended to prepare fresh working solutions just before use. Avoid multiple freeze-thaw cycles to maintain optimal biological activity.

Buffer: Lyophilized from double distilled water (ddH2O). May contain residual trifluoroacetate (TFA).

Conseil sur la manipulation: Centrifuge the vial at 10,000 x g for 5 minutes before opening to ensure all material is collected at the bottom,Avoid multiple freeze-thaw cycles to maintain optimal biological activity,Avoid vigorous vortexing. protect from moisture

Stock: -20 °C

Stockage commentaire: The product is shipped as a lyophilized powder at room temperature. Upon receipt, store at -20°C and protect from moisture.

Détail du antigène

Antigène: MitTx Toxin

Sujet: An activator of ASIC1-containing channels

Poids moléculaire: 20.84 kDa (i± subunit, 7.104 kDa and i² subunit, 13.736 kDa)

UniProt: G9I930, G9I929