Pardaxin Protéine

N° du produit ABIN7582349

Cette protéine Native Pardaxin est produite dans Fish.

Aperçu rapide pour Pardaxin Protéine (ABIN7582349)

Antigène: Pardaxin

Type de proteíne: Native

Origine: Pardachirus marmoratus

Source: Fish

Application: Blocking Peptide (BP)

Pureté: ≥98 % (HPLC)

Détail du produit

Fonction: An Inducer of Neurotransmitter Release

Séquence: GFFALIPKII SSPLFKTLLS AVGSALSSSG DQE-OH

Attributs du produit: An Inducer of Neurotransmitter Release

Information d'application

Indications d'application: Antigen Preadsorption Control: 1 - 10 μM

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the vial (10,000 x g for 5 minutes) before adding solvent to spin down all the powder to the bottom of the vial. The lyophilized product may be difficult to visualize. Add solvent directly to the centrifuged vial. Gently tap, tilt, and roll the vial to aid dissolution. Avoid vigorous vortexing, light vortexing for up to 3 seconds is acceptable if needed. The product is soluble in pure water at high micromolar concentrations (100 μM - 1 mM). For long-term storage in solution, we recommend preparing a stock solution by dissolving the product in double-distilled water (ddH2O) at a concentration between 100-1000x of the final working concentration. Divide the stock solution into small aliquots and store at -20 °C. Before use, thaw the relevant vial(s) and dilute to the desired working concentration in your working buffer. Centrifuge all product preparations before use. It is recommended to prepare fresh solutions in working buffers just before use. Avoid multiple freeze-thaw cycles to maintain biological activity.

Buffer: Lyophilized from double distilled water (ddH2O). May contain TFA as a residual counter ion.

Stock: 4 °C,-20 °C

Stockage commentaire: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods (up to 6 months), small aliquots should be stored at -20°C. We do not recommend storing the product in working solutions for longer than a few days. Avoid multiple freeze-thaw cycles.,The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods (up to 6 months), small aliquots should be stored at -20°C. We do not recommend storing the product in working solutions for longer than a few days. Avoid multiple freeze-thaw cycles.

Détail du antigène

Antigène: Pardaxin

Sujet: Pardaxin P-5, Pardaxin Pa5, Pardaxin P5,Pardaxin is a 33 amino acid peptidyl toxin, produced by the Red Sea Moses sole fish Pardachirus marmoratus. Pardaxin is acidic, amphipathic, and hydrophobic that forms voltage-dependent pore channels in liposomes and planar lipid bilayers and living cells2.The toxin exhibits a neurotoxic, excitatory activity toward neurons at subcytotoxic concentrations by both Ca2+-dependent and Ca2+-independent mechanisms. Pardaxin also causes hemolysis, reduction of blood pressure, cell death by necrosis, and is lethal to rats at higher concentrations3.

Poids moléculaire: 3382 Da

UniProt: P81862