CD200 Protein (CD200) (AA 31-232) (hIgG-His-tag)
Aperçu rapide pour CD200 Protein (CD200) (AA 31-232) (hIgG-His-tag) (ABIN7596333)
Antigène
Voir toutes CD200 ProtéinesType de proteíne
Origine
Source
Application
Pureté
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Attributs du protein
- AA 31-232
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Purification/Conjugué
- Cette CD200 protéine est marqué à la hIgG-His-tag.
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Séquence
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QVEVVTQDER KALHTTASLR CSLKTSQEPL IVTWQKKKAV SPENMVTYSK THGVVIQPAY KDRINVTELG LWNSSITFWN TTLEDEGCYM CLFNTFGSQK VSGTACLTLY VQPIVHLHYN YFEDHLNITC SATARPAPAI SWKGTGTGIE NSTESHFHSN GTTSVTSILR VKDPKTQVGK EVICQVLYLG NVIDYKQSLD KG
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niveau d'endotoxine
- < 1 EU per 1ug of protein (determined by LAL method)
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- CD200
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Autre désignation
- CD200
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Sujet
- CD200, also known as OX-2 membrane glycoprotein isoform 1, is one of the immunoglobulin superfamily. It plays an important role in anti-tumor immunity through interaction with its receptor, and overexpression of this protein effects on malignancies as well as on cancer stem cells. In T cells, this protein functions as a co-stimulatory effect that is independent of the CD28 pathway. It also plays an important role on myeloid cell regulation that is suggested by restricted expression of its receptor. Studies of this protein in mouse and rat suggest that this gene may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Recombinant mouse CD200, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
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Poids moléculaire
- 49.5 kDa (441aa)
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NCBI Accession
- NP_034948
Antigène
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