CD9 Protein (CD9) (AA 112-195) (hIgG-His-tag)
Aperçu rapide pour CD9 Protein (CD9) (AA 112-195) (hIgG-His-tag) (ABIN7596342)
Antigène
Voir toutes CD9 ProtéinesType de proteíne
Origine
Source
Application
Pureté
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Attributs du protein
- AA 112-195
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Purification/Conjugué
- Cette CD9 protéine est marqué à la hIgG-His-tag.
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Séquence
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SHKDEVI KEVQEFYKDT YNKLKTKDEP QRETLKAIHY ALNCCGLAGG VEQFISDICP KKDVLETFTV KSCPDAIKEV FDNKFHI -
niveau d'endotoxine
- < 1 EU per 1ug of protein (determined by LAL method)
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- CD9
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Autre désignation
- CD9
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Sujet
- CD9, also known as TSPAN-29, is a member of tetraspanin family. It is found on the surface of exosomes. It can modulate cell adhesion and migration and also trigger platelet activation and aggregation. In addition, the protein appears to promote muscle cell fusion and support myotube maintenance. It seems CD9 has a varying role in different types of cancers. The over expression of CD9 was shown to decrease metastasis in certain types of melanoma, breast, lung, pancreas and colon carcinomas. However in other studies, CD9 has been shown to increase migration or be highly expressed in metastatic cancers in various cell lines such as lung cancer, scirrhous-type gastric cancer, hepatocellular carcinoma, acute lymphoblastic leukemia and breast cancer. Recombinant human CD9, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
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Poids moléculaire
- 36.9kDa (326aa)
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NCBI Accession
- NP_001760
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Pathways
- Response to Water Deprivation, Cell-Cell Junction Organization
Antigène
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