CCR3 Protéine

N° du produit ABIN7597219

Cette protéine MNP Membrane Nanoparticle CCR3 est produite dans HEK-293 Cells.

Aperçu rapide pour CCR3 Protéine (ABIN7597219)

Antigène: CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))

Type de proteíne: MNP Membrane Nanoparticle

Origine: Humain

Source: HEK-293 Cells

Détail du produit

Fonction: Human CCR3 full length protein-MNP

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from PBS. Normally 5% – 8% trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))

Autre désignation: CCR3

Sujet: CC-CKR-3, C C CKR3, CD193, CKR 3, CKR3, CMKBR3
The protein is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described.

Poids moléculaire: The human full length CCR3 protein has a MW of 41.0 kDa

UniProt: P51677