DKK3 Protein (AA 22-350) (Fc Tag)

N° du produit ABIN7597408

Cette protéine Recombinant DKK3 est produite dans HEK-293 Cells.

Aperçu rapide pour DKK3 Protein (AA 22-350) (Fc Tag) (ABIN7597408)

Antigène: DKK3

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Pureté: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Détail du produit

Attributs du protein: AA 22-350

Purification/Conjugué: Cette DKK3 protéine est marqué à la Fc Tag.

Fonction: Recombinant human DKK3 Protein with C-terminal human Fc tag

Séquence: DKK3(Ala22-Ile350) hFc(Glu99-Ala330)

Information d'application

Indications d'application: Extracellular Domain Proteins (ECD) can be used as:

• Immunogens for antibody drug development
• Reagents used for CAR-T positive cell monitoring
• Reagents for antibody screening and functional testing
• Reagents for antibody affinity measurement

Commentaires:

The protein was made using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: DKK3

Sujet: RIG, CRRL, REIC
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]

Poids moléculaire: predicted molecular mass of 62.4 kDa after removal of the signal peptide. The apparent molecular mass of DKK3-hFc is 70-130 kDa due to glycosylation.

UniProt: Q9UBP4