A1BG Protein (His tag)

N° du produit ABIN7668143

Cette protéine Recombinant A1BG est exprimée dans HEK-293 Cells.

Aperçu rapide pour A1BG Protein (His tag) (ABIN7668143)

Antigène: A1BG (alpha-1-B Glycoprotein (A1BG))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Pureté: > 95 % as determined by reducing SDS-PAGE.

Détail du produit

Purification/Conjugué: Cette A1BG protéine est marqué à la His tag.

Fonction: Recombinant Human A1BG/alpha 1B-Glycoprotein Protein (His Tag)

Séquence: Met 1-Ser495

Purification: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: A1BG (alpha-1-B Glycoprotein (A1BG))

Autre désignation: A1BG

Sujet: A1B,ABG,GAB,HYST2477,Alpha-1B-glycoprotein (A1BG) is an approximately 80 kDa molecule that circulates in the serum. Mature human A1BG consists of five tandem Ig like domains and shares 44 % amino acid sequence identity with mouse and rat A1BG. Alternative splicing generates an isoform that lacks the signal peptide and the first Ig like domain. A1BG binds with high affinity to the cysteine rich protein CRISP-3. In pancreatic carcinoma, it is elevated in pancreatic juice as well as in the serum relative to normal patients. A1BG is abnormally excreted into the urine during idiopathic nephrotic syndrome (INS). Multiple breakdown fragments of A1BG are also present in INS urine, including one of 14 kDa that is found in steroid resistant but not steroid sensitive cases. A1BG is also elevated in the urine of patients with interstitial cystitis/painful bladder syndrome (IC/PBS).

Poids moléculaire: 53.4 kDa

ID gène: 1

UniProt: P04217