AMH Protein (AA 447-554) (His-TRX)

N° du produit ABIN7668182

Cette protéine Recombinant AMH est exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour AMH Protein (AA 447-554) (His-TRX) (ABIN7668182)

Antigène: AMH (Anti-Mullerian Hormone (AMH))

Type de proteíne: Recombinant

Activité biologique: Inactive

Origine: Souris

Source: Escherichia coli (E. coli)

Pureté: > 95 %

Détail du produit

Attributs du protein: AA 447-554

Purification/Conjugué: Cette AMH protéine est marqué à la His-TRX.

Fonction: Recombinant Mouse AMH protein (TRX,His tag)

Séquence: Ser447-Val554

Purification: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: < 10 EU/mg of the protein as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % -8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: AMH (Anti-Mullerian Hormone (AMH))

Autre désignation: AMH

Sujet: Anti-Mullerian hormone (AMH), a member of the TGF-beta superfamily, is produced by granulosa cells (GCs) of preantral and small antral follicles and plays a role in regulating the recruitment of primordial follicles and the FSH-dependent development of follicles. BMP15 up-regulates the transcription of AMH and that the inhibition of p38 MAPK decreases the BMP15-induced expression of AMH and SOX9, suggesting that BMP15 up-regulates the expression of AMH via the p38 MAPK signaling pathway, and this process involves the SOX9 transcription factor. AMH is widely used for assessing ovarian reserve, and it is particularly convenient, because it is thought to have minimal variability throughout the menstrual cycle. Fetal anti-Mullerian hormone (AMH) is responsible for normal male sexual differentiation, and circulating AMH is used as a marker of testicular tissue in newborns with disorders of sex development. Anti-Mullerian hormone (AMH) produced in the developing testis induces the regression of the Mullerian duct, which develops into the oviducts, uterus and upper vagina. As well as other hormone receptors, and a decreased ovarian cortex cell proliferation. These results help understand the inhibitory effects of AMH on follicular development.,Amh,Anti-Muellerian hormone,Muellerian-inhibiting factor,Muellerian-inhibiting substance

Poids moléculaire:

calculated_mw: 31.8 kDa

observed_mw: 35 kDa

UniProt: P27106

Pathways: Negative Regulation of Hormone Secretion