CBLC Protein (His-GST)
Aperçu rapide pour CBLC Protein (His-GST) (ABIN7668326)
Antigène
Voir toutes CBLC ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
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Purification/Conjugué
- Cette CBLC protéine est marqué à la His-GST.
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Fonction
- Recombinant Human Cbl-c/CBL-3 Protein (His & GST Tag)
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Séquence
- Met 1-Ala474
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Purification
- > 95 % as determined by reducing SDS-PAGE.
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Stérilité
- 0.2 μm filtered
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niveau d'endotoxine
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
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Lyophilized from sterile 20 mM Tris, 500 mM Nacl, 10 % glycerol, pH 8.0
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Date de péremption
- 12 months
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- CBLC (Cbl proto-oncogene C (CBLC))
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Autre désignation
- Cbl-c
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Sujet
- CBL proteins, such as Cbl-c, are phosphorylated upon activation of a variety of receptors that signal via protein tyrosine kinases. Through interactions with proteins containing SRC homology-2 (SH2) and SH3 domains, CBL proteins modulate downstream cell signaling. Cbl-c is a member of the Cbl family of E3 ubiquitin ligases. Expression of Cbl-c gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for Cbl-c gene.,CBL-3,CBL-SL,RNF57
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Poids moléculaire
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calculated_mw: 80.2 kDa
observed_mw: 66 kDa
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UniProt
- Q9ULV8
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Pathways
- EGFR Signaling Pathway
Antigène
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