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CD5 Protein (CD5) (His tag)

Cette protéine Recombinant CD5 est produite dans Escherichia coli (E. coli).
N° du produit ABIN7668385

Aperçu rapide pour CD5 Protein (CD5) (His tag) (ABIN7668385)

Antigène

Voir toutes CD5 Protéines
CD5

Type de proteíne

Recombinant

Activité biologique

Inactive

Origine

  • 19
  • 5
  • 4
  • 2
  • 1
Rat

Source

  • 19
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Pureté

> 95 %
  • Purification/Conjugué

    Cette CD5 protéine est marqué à la His tag.

    Fonction

    Recombinant Rat CD5 / Cluster of Differentiation 5 protein (His tag)

    Séquence

    Ser 25-Pro 368

    Purification

    > 95 % as determined by reducing SDS-PAGE.

    Stérilité

    0.2 μm filtered

    niveau d'endotoxine

    < 10 EU/mg of the protein as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

    Buffer

    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % -8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

    Stock

    4 °C,-20 °C,-80 °C

    Stockage commentaire

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    Date de péremption

    12 months
  • Antigène

    CD5

    Autre désignation

    CD5

    Sujet

    The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD5 is a member of the CD system. CD5 was found to be widely distributed in T-cells and B1 cells which is a subset of IgM-secreting B cells. CD5 also was found expressed in small lymphocytic lymphoma, hairy cell leukaemia and mantle cell lymphoma cells. CD5 serves to weaken the activating stimulus from the BCR so that the B1 cells can only reflect to the very strong stimuli but not the normal tissue proteins.,Cd5,T-cell surface glycoprotein CD5

    Poids moléculaire

    calculated_mw: 37.7 kDa

    observed_mw: 42 kDa

    UniProt

    P51882
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