CCL17 Protein (Fc Tag)

N° du produit ABIN7668432

Protéine Recombinant CCL17 exprimée dans Mammalian Cells.

Aperçu rapide pour CCL17 Protein (Fc Tag) (ABIN7668432)

Antigène: CCL17 (Chemokine (C-C Motif) Ligand 17 (CCL17))

Type de proteíne: Recombinant

Activité biologique: Inactive

Origine: Humain

Source: Mammalian Cells

Pureté: > 90 %

Détail du produit

Purification/Conjugué: Cette CCL17 protéine est marqué à la Fc Tag.

Fonction: Recombinant human TARC Protein(Fc Tag)

Séquence: Met 1-Ser 94

Purification: SDS-PAGE analysis of Human TARC proteins, 2 μg/lane of Recombinant Human TARC proteins was resolved with an SDS-PAGE under reducing conditions, showing bands at 35.2 KD

Stérilité: 0.2 μm filtered

niveau d'endotoxine: < 1.0 EU/mg of the protein as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with 5 % Trehalose and 5 % Mannitol.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: CCL17 (Chemokine (C-C Motif) Ligand 17 (CCL17))

Autre désignation: TARC

Sujet: Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokin ligand 17 (CCL17), also known as thymus and activation regulated chemokine(TARC), is a small cytokine belonging to the C-C chemokine family. CCL17 is expressed maily in thymus and transiently in phytohemagglutinin-stimulated peripheral blood mononuclear cells. CCL17 can induce chemotaxis in T cells by binding with the chemokine receptor CCR4.,A-152E5.3,A152E53,ABCD 2,ABCD2,C-C motif chemokine 17,CC chemokine TARC,CCL17,CCL17,Chemokine CC Motif Ligand 17,MGC138271,MGC138273,SCYA17,Small Inducible Cytokine A17,Small Inducible Cytokine A17 Precursor,Small Inducible Cytokine Subfamily A (Cys Cys),Small Inducible Cytokine Subfamily A (Cys Cys) Member 17,Small-inducible cytokine A17,T Cell Directed CC Chemokine,Thymus and activation regulated chemokine,Thymus and activation-regulated chemokine

Poids moléculaire:

calculated_mw: 35.2 kDa

observed_mw: 36 kDa

UniProt: Q92583