Hepcidin Protein (AA 59-83) (His-TRX)

N° du produit ABIN7668892

Cette protéine Recombinant Hepcidin est produite dans Escherichia coli (E. coli).

Aperçu rapide pour Hepcidin Protein (AA 59-83) (His-TRX) (ABIN7668892)

Antigène: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Type de proteíne: Recombinant

Activité biologique: Inactive

Origine: Souris

Source: Escherichia coli (E. coli)

Pureté: > 95 %

Détail du produit

Attributs du protein: AA 59-83

Purification/Conjugué: Cette Hepcidin protéine est marqué à la His-TRX.

Fonction: Recombinant Mouse Hepcidin/Hepc protein (TRX,His tag)

Séquence: Asp59-Thr83

Stérilité: 0.2 μm filtered

niveau d'endotoxine: < 10 EU/mg of the protein as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % -8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Autre désignation: Hepcidin,Hepc

Sujet: Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes.,HEPC_MOUSE,Hamp,Hamp1,Hepc,Hepc1,Hepcidin

Poids moléculaire:

calculated_mw: 22.6 kDa

observed_mw: 25 kDa

UniProt: Q9EQ21

Pathways: Hormone Activity, Transition Metal Ion Homeostasis