IgG4 Protein (AA 99-327) (His tag)

N° du produit ABIN7668933

Protéine Recombinant IgG4 exprimée dans HEK-293 Cells.

Aperçu rapide pour IgG4 Protein (AA 99-327) (His tag) (ABIN7668933)

Antigène: IgG4

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Application: Immunogen (Imm)

Pureté: > 95 % as determined by reducing SDS-PAGE.

Détail du produit

Attributs du protein: AA 99-327

Purification/Conjugué: Cette IgG4 protéine est marqué à la His tag.

Fonction: Recombinant Human IgG4-Fc Protein (His Tag)

Séquence: Glu99-Lys327

Purification: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: < 1.0 EU/mg of the protein as determined by the LAL method

Biological Activity Comment: Not validated for activity

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with 5 % Trehalose and 5 % Mannitol.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: IgG4

Classe de substances: Antibody

Sujet: IGHG4,Ig gamma-4 chain C region,IgG4 Fc,SCN3B (sodium channel, voltage-gated, type III, beta,human IgG1-Fc chimera) belongs to the sodium channel auxiliary subunit SCN3B family. It contains 1 Ig-like C2-type (immunoglobulin-like) domain. Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. SCN3B gene encodes one member of the sodium channel beta subunit gene family, and influences the inactivation kinetics of the sodium channel. Two alternatively spliced variants, encoding the same protein, have been identified. Defects in SCN3B are the cause of Brugada syndrome type 7. A tachyarrhythmia characterized by right bundle branch block and ST segment elevation on an electrocardiogram. It can cause the ventricles to beat so fast that the blood is prevented from circulating efficiently in the body. When this situation occurs (called ventricular fibrillation), the individual will faint and may die in a few minutes if the heart is not reset.

Poids moléculaire:

Calculated MW: 25.1 kDa

Observed MW: 35 kDa

UniProt: P01861