Nectin-4 (NECTIN4) (Inactive) protein (His tag)

N° du produit ABIN7669348

Cette protéine Recombinant est produite dans Escherichia coli (E. coli).

Aperçu rapide pour Nectin-4 (NECTIN4) (Inactive) protein (His tag) (ABIN7669348)

Antigène: Nectin-4 (NECTIN4)

Type de proteíne: Recombinant

Activité biologique: Inactive

Origine: Humain

Source: Escherichia coli (E. coli)

Pureté: > 95 %

Détail du produit

Purification/Conjugué: His tag

Fonction: Recombinant Human Nectin-4/NECTIN4 protein (His tag)

Séquence: Gly 32-Leu 146

Purification: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: < 10 EU/mg of the protein as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % -8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: Nectin-4 (NECTIN4)

Autre désignation: Nectin-4,NECTIN4

Sujet: Nectin-4 (PVRL4) is a type I transmembrane glycoprotein which belongs to the nectin family of Ig superfamily proteins. It contains two Ig-like C2-type domains and one Ig-like V-type domain. PVRL4 seems to be involved in cell adhesion through trans-homophilic and-heterophilic interactions, the latter including specifically interactions with nectin-1. It does not act as receptor for alpha-herpesvirus entry into cells. It is predominantly expressed in placenta, the embryo and breast carcinoma. But it is not detected in normal breast epithelium. The soluble form is produced by proteolytic cleavage at the cell surface (shedding), probably by ADAM17. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder.,Ig superfamily receptor LNIR,LNIR,Nectin-4,PRR4,PVRL4,Poliovirus receptor-related protein 4

Poids moléculaire:

calculated_mw: 12.5 kDa

observed_mw: 15 kDa

UniProt: Q96NY8