Occludin Protein (OCLN) (His tag)

N° du produit ABIN7669390

Cette protéine Recombinant Occludin est produite dans Escherichia coli (E. coli).

Aperçu rapide pour Occludin Protein (OCLN) (His tag) (ABIN7669390)

Antigène: Occludin (OCLN)

Type de proteíne: Recombinant

Activité biologique: Inactive

Origine: Humain

Source: Escherichia coli (E. coli)

Pureté: > 90 %

Détail du produit

Purification/Conjugué: Cette Occludin protéine est marqué à la His tag.

Fonction: Recombinant Human OCLN Protein(His Tag)

Séquence: Lys266~Thr522

Purification: SDS-PAGE analysis of Human OCLN proteins, 2 μg/lane of Recombinant Human OCLN proteins was resolved with an SDS-PAGE under reducing conditions, showing bands at 28 KD

Stérilité: 0.2 μm filtered

niveau d'endotoxine: < 10 EU/mg of the protein as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with 5 % Trehalose and 5 % Mannitol.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: Occludin (OCLN)

Autre désignation: OCLN

Sujet: This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with an simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.,BLCPMG,FLJ08163,FLJ18079,FLJ77961,FLJ94056,MGC34277,Occludin,Ocln,OCLN,Phosphatase 1 regulatory subunit 115,PPP1R115,PTORCH1,Tight junction protein occludin

Poids moléculaire:

calculated_mw: 28 kDa

observed_mw: 42 kDa

UniProt: Q16625

Pathways: Cell-Cell Junction Organization, Hepatitis C