VEGF (Aflibercept Biosimilar) Protein (Fc Tag)

N° du produit ABIN7795087

Cette protéine Recombinant VEGF (Aflibercept Biosimilar) est exprimée dans CHO Cells.

Aperçu rapide pour VEGF (Aflibercept Biosimilar) Protein (Fc Tag) (ABIN7795087)

Antigène: VEGF (Aflibercept Biosimilar)

Type de proteíne: Recombinant

Origine: Humain

Source: CHO Cells

Application: In vivo Studies (in vivo)

Pureté: >95% by SDS-PAGE under reducing conditions and HPLC

Classe de qualité: Research Grade

Détail du produit

Purification/Conjugué: Cette VEGF (Aflibercept Biosimilar) protéine est marqué à la Fc Tag.

Fonction: Recombinant protein composed of the binding domains of two human vascular endothelial growth factor (VEGF) receptors fused with the Fc region of human immunoglobulin gamma 1 (hIgG1).

Specificité: The aflibercept biosimilar protein specifically binds to the human VEGF.

Attributs du produit: Research grade Aflibercept biosimilar has the same amino acid sequence as Aflibercept (trade name Eylea), a recombinant protein composed of the binding domains of two human vascular endothelial growth factor (VEGF) receptors fused with the Fc region of human immunoglobulin gamma 1 (IgG1). It inhibits vascular endothelial growth factor (VEGF), and is used in the treatment of macular edema following Central Retinal Vein Occlusion (CRVO) and neovascular Age-Related Macular Degeneration (AMD). Aflibercept is a dimeric glycoprotein with a molecular weight of 96.9 kilo Daltons (kDa). Glycosylation adds its molecular weight to 115 kDa in total. Ziv-aflibercept (trade name Zaltrap) was developed as an injection for treatment of metastatic colorectal cancer.

Purification: The aflibercept biosimilar protein was produced in CHO stable cell line.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: < 1 EU per 1 mg of the protein by the LAL method

Information d'application

Indications d'application: Functional assays, and those assays for studying biological pathways affected by aflibercept.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: pH 6.1, no stabilizers or preservatives

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.

Date de péremption: 12 months

Détail du antigène

Antigène: VEGF (Aflibercept Biosimilar)

Autre désignation: Aflibercept Biosimilar

Classe de substances: Biosimilar