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MUC1 Protéine

Protéine Native MUC1 exprimée dans Human.
N° du produit ABIN7849659
1.045,00 €
Plus frais de livraison 40,00 € et TVA
50 kU
Destination: France
Envoi sous 9 à 11 jours ouvrables

Aperçu rapide pour MUC1 Protéine (ABIN7849659)

Antigène

Voir toutes MUC1 Protéines
MUC1 (Mucin 1 (MUC1))

Type de proteíne

Native

Origine

  • 26
  • 6
  • 4
  • 3
  • 3
Humain

Source

  • 20
  • 13
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Application

SDS-PAGE (SDS)

Pureté

>60 % by SDS-PAGE
  • Fonction

    Native Human CA153 Protein
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  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    10 mM PBS, pH 7.4±0.2 with 0.2 % Sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Ship at 4°C.Upon receipt, aliquot andstore at -20°C for long term. Avoid repeated freeze and thaw cycles.
  • Antigène

    MUC1 (Mucin 1 (MUC1))

    Autre désignation

    CA153

    Sujet

    Synonyms: KL-6, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, Breast carcinoma associated antigen DF3, CA15-3 antigen, CA15.3, Carcinoma associated mucin, CD 227, CD227, CD227 antigen, DF3 antigen, EMA, Episialin, Epithelial membrane antigen, Epithelial mucin tandem repeat sequence, H23 antigen, H23AG, MAM6, MUC 1, MUC-1, Mucin 1, Mucin 1 precursor, Mucin1, Peanut reactive urinary mucin, PEM, PEMT, Polymorphic epithelial mucin, PUM, Tumor associated epithelial membrane antigen, Tumor associated mucin

    Description: Purified human Cancer Antigen CA15-3 protein.

    Background: CA 15-3, for Carcinoma Antigen 15-3, is a tumor marker for many types of cancer, most notably breast cancer. It is derived from MUC1. CA 15-3 and associated CA 27-29 are different epitopes on the same protein antigen product of the breast cancer-associated MUC1 gene. Elevated CA15-3, in conjunction with alkaline phosphatase (ALP), was found to be associated with an increased chance of early recurrence in breast cancer. Both CA 15-3 and CA 27-29 may be elevated in patients with benign ovarian cysts, benign breast disease, and benign liver disease. Elevations may also be seen in cirrhosis, sarcoidosis and lupus.

    Pathways

    Negative Regulation of intrinsic apoptotic Signaling
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