Creatine Kinase MB Protein (CKM)

N° du produit ABIN7849673

Cette protéine Native Creatine Kinase MB est exprimée dans Human.

Aperçu rapide pour Creatine Kinase MB Protein (CKM) (ABIN7849673)

Antigène: Creatine Kinase MB (CKM)

Type de proteíne: Native

Origine: Humain

Source: Human

Application: Immunoassay (IA)

Détail du produit

Fonction: Native Human Creatine kinase MB,CK-MB protein

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 20 mM Tris-HCl pH 8.0, 5 mM beta Mercaptoethano and 6 % Sugrose.

Stock: 4 °C,-20 °C

Stockage commentaire: Ship at 4°C.Upon receipt, aliquot and store at -20°C for long term. Avoid repeated freeze and thaw cycles.

Détail du antigène

Antigène: Creatine Kinase MB (CKM)

Autre désignation: Creatine kinase MB

Sujet:

Synonyms: CK-MB, B-CK, brain creatine kinase, CKBB, CKMB, CKMM, creatine kinase B, creatine kinase brain, creatine kinase M, Creatine kinase MB, Creatine Kinase MB type, creatine kinase muscle, M-CK, creatine kinase-M/B, KCRB_HUMAN, muscle creatine kinase

Description: Purified Creatine Kinase-MB Isoenzyme Protein.

Background: Creatine kinase isoenzyme-MB (CK-MB) is a biomarker for detecting myocardial injury. It is a simple, widely available, and useful biomarker for predicting adverse in-hospital clinical outcomes in pulmonary embolism. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The CK-MB-to-total-CK ratio is an easily available indicator and could be clinically utilized as a primary screening tool for cancer. Higher ratio of CK-MB-to-total-CK was specifically associated with certain malignancies, like colorectal cancer, lung cancer and hepatocellular carcinoma, as well as some cancer-associated status factors such as advanced stage and liver metastasis.