CKM Protéine

N° du produit ABIN7849674

Protéine Recombinant CKM exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour CKM Protéine (ABIN7849674)

Antigène: CKM (Creatine Kinase, Muscle (CKM))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Application: ELISA

Pureté: >90 % by SDS-PAGE

Détail du produit

Fonction: Recombinant Human Creatine kinase muscle,CK-MMprotein

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 20 mM Tris-HCl pH 8.0.

Stock: 4 °C,-20 °C

Stockage commentaire: Ship at 4°C. Upon receipt, aliquot and store at -20°C for long term. Avoid repeated freeze and thaw cycles.

Détail du antigène

Antigène: CKM (Creatine Kinase, Muscle (CKM))

Autre désignation: Creatine kinase muscle,CK-MM

Sujet:

Synonyms: CKM, CKMM, creatine kinase M, Creatine kinase M type, creatine kinase muscle, creatine kinase muscle type, Creatine Kinase M-type, M-CK, MCK.

Description: Recombinant creatine kinasemuscle type,CK-MM Protein.

Background: Creatine kinase (CK), also known as creatine phosphokinase (CPK) or phospho-creatine kinase (and sometimes incorrectly as creatinine kinase), is an enzyme expressed by various tissues and cell types. CK catalyses the conversion of creatine and consumes adenosine triphosphate (ATP) to create phosphocreatine (PCr) and adenosine diphosphate (ADP). This CK enzyme reaction is reversible and thus ATP can be generated from PCr and ADP. In the cells, the "cytosolic" CK enzymes consist of two subunits, which can be either B (brain type) or M (muscle type). There are, therefore, three different isoenzymes: CK-MM, CK-BB and CK-MB. The genes for these subunits are located on different chromosomes: B on 14q32 and M on 19q13. In heart, in addition to the MM-CK homodimer also the heterodimer consisting of one muscle (MM-CK) and one brain-type (MB-CK) subunit is expressed. This latter is an important serum marker for myocardial infarction, for it is released from damaged myocardial cells into the blood where it can be detected by clinical chemistry.