CST3 Protéine

N° du produit ABIN7849680

Protéine Recombinant CST3 exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour CST3 Protéine (ABIN7849680)

Antigène: CST3 (Cystatin C (CST3))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Pureté: >85 % by SDS-PAGE

Détail du produit

Fonction: Recombinant Human Cystatin C Protein

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Ship at 4°C. Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.

Détail du antigène

Antigène: CST3 (Cystatin C (CST3))

Autre désignation: Cystatin C

Sujet: Optional[Synonyms]: Cystatin C or cystatin 3 (formerly gamma trace, post-gamma-globulin, or neuroendocrine basic polypeptide), a protein encoded by the CST3 gene, is mainly used as a biomarker of kidney function. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid (a specific type of protein deposition), such as Alzheimer's disease. In humans, all cells with a nucleus (cell core containing the DNA) produce cystatin C as a chain of 120 amino acids. It is found in virtually all tissues and body fluids. It is a potent inhibitor of lysosomal proteinases (enzymes from a special subunit of the cell that break down proteins) and probably one of the most important extracellular inhibitors of cysteine proteases (it prevents the breakdown of proteins outside the cell by a specific type of protein degrading enzymes). Cystatin C belongs to the type 2 cystatin gene family.