IL-31 Protein (His tag)

N° du produit ABIN7884497

Cette protéine Recombinant IL-31 est exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour IL-31 Protein (His tag) (ABIN7884497)

Antigène: IL-31 (IL31) (Interleukin 31 (IL31))

Type de proteíne: Recombinant

Origine: Souris

Source: Escherichia coli (E. coli)

Application: Western Blotting (WB)

Pureté: >98 %

Détail du produit

Purification/Conjugué: Cette IL-31 protéine est marqué à la His tag.

Fonction: IL-31 (Interleukin-31), Mouse

Séquence: MTCSLSFGAP ISKEDLRTTI DLLKQESQDL YNNYSIKQAS GMSADESIQL PCFSLDREAL TNISVIIAHL EKVKVLSENT VDTSWVIRWL TNISCF NPLNLNISVP GNTDESYDCK VFVLTVLKQF SNCMAELQAK DNTTC with polyhistid ine tag at the Cterminus

niveau d'endotoxine: <0.1 EU per 1 μg protein

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: dissolve in sterile H2O

Buffer: PBS, pH 7.4

Stock: -20 °C

Stockage commentaire: -20°C

Détail du antigène

Antigène: IL-31 (IL31) (Interleukin 31 (IL31))

Autre désignation: IL-31

Sujet: Interleukin-31 (IL-31) s an inflammatory cytokine that helps trigger cell-mediated immunity against pathogens. It has also been identified as a major player in a number of chronic inflammatory diseases, including atopic dermatitis. It is produced by a variety of cells, namely type 2 helper (TH2) T-cells. IL-31 sends signals through a receptor complex made of IL-31RA and oncostatin M receptor β (OSMRβ) expressed in immune and epithelial cells. These signals activate three pathways: ERK1/2 MAP kinase, PI3K/AKT, and JAK1/2 signaling pathways.

Poids moléculaire: 18kDa

ID gène: 76399

NCBI Accession: NP_083870

UniProt: Q6EAL8