LTA Protein (His tag)
Aperçu rapide pour LTA Protein (His tag) (ABIN7884535)
Antigène
Voir toutes LTA ProtéinesType de proteíne
Activité biologique
Origine
Source
Application
Pureté
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Purification/Conjugué
- Cette LTA protéine est marqué à la His tag.
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Fonction
- TNF beta (Tumor necrosis factor-β), Human
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Séquence
- LPGVGLTPSA AQTARQHPKM HLAHSTLKPA AHLIGDPSKQ NSLLWRANTD RAFLQDGFSL SNNSLLVPTS GIYFVYSQVV FSGKAYSPKA TS SPLYLAHEVQ LFSSQYPFHV PLLSSQKMVY PGLQEPWLHS MYHGAAFQLT QGDQLSTHTD GIPHLVLSPS TVFFGAFAL with polyhistid ine tag at the N-terminus
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niveau d'endotoxine
- <0.1 EU per 1 μg protein
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Biological Activity Comment
- >3.3 x 108 IU/mg
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Lymphotoxin-alpha (LTA) (AA 58-205) protein (His-DYKDDDDK-Strep II Tag)
LTA Origine: Humain Hôte: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
Lymphotoxin-alpha (LTA) (Active) proteinLTA Origine: Chemical Hôte: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Lymphotoxin-alpha (LTA) (AA 1-205) protein (GST tag)LTA Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Lymphotoxin-alpha (LTA) (AA 35-205) protein (His tag)LTA Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Lymphotoxin-alpha (LTA) (AA 34-202) protein (His tag)LTA Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Lymphotoxin-alpha (LTA) (AA 35-205) (Active) protein (His tag)LTA Origine: Humain Hôte: Baculovirus infected Insect Cells Recombinant > 90 % SDS, AcA Active
Lymphotoxin-alpha (LTA) (AA 35-205) (Active) protein (His tag)LTA Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS, AcA Active
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- dissolve in sterile H2O
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Buffer
- pH 3.5
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Stock
- -20 °C
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Stockage commentaire
- -20°C
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- LTA (Lymphotoxin-alpha (LTA))
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Autre désignation
- TNF beta
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Sujet
- TNF-β works as a potential mediator in the inflammatory and immune process. It a component of the TNF family of ligands, and signals through TNFR1 and TNFR2. TNF-β is secreted by activated T and B lymphocytes, and has similar function to TNF-α. In the same manner as TNF-α, TNF-β is involved in the regulation of various biological processes, including cell proliferation, differentiation, apoptosis, lipid metabolism, coagulation, and neurotransmission. TNF-β is generally released as a soluble polypeptide. In addition, lymphotoxin-β can anchor TNF-β to the cell surface and form heterotrimers in an effective manner. TNF-β is cytotoxic to a wide range of tumor cells.
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Poids moléculaire
- 22kDa
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ID gène
- 4049
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NCBI Accession
- NP_000586
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UniProt
- P01374
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Antigène
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