CTBP1 Protéine
Aperçu rapide pour CTBP1 Protéine (ABIN7938668)
Antigène
Voir toutes CTBP1 ProtéinesType de proteíne
Origine
Source
Application
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Fonction
- Recombinant CTBP1 protein
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Attributs du produit
- CTBP1 (C-Terminal Binding Protein 1), also written as CtBP1, is a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. It is a corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. It also has dehydrogenase activity. It is involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex, and has functions in brown adipose tissue (BAT) differentiation.
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Recombinant CTBP1 protein is supplied in 25 mM Tris-HCl pH 8.0, 500 mM NaCl, 10 % glycerol, 0.5 mM TCEP.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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Stock
- -80 °C
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Stockage commentaire
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- CTBP1 (C-terminal Binding Protein 1 (CTBP1))
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Autre désignation
- CTBP1
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Sujet
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Protein Background: CTBP1 (C-Terminal Binding Protein 1), also written as CtBP1, is a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. It's a corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. It also has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation.
Short Description: Recombinant CTBP1 protein was expressed in E.coli as the full length protein (accession number (NP_001319.1) with an N-terminal 6x-His Tag. The molecular weight of the protein is 51.1 kDa.
Aliases: C-terminal Binding Protein, BARS
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Pathways
- Retinoic Acid Receptor Signaling Pathway
Antigène
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