CDK2/CyclinA2 (Complex) Protéine

N° du produit ABIN7938689

Cette protéine Recombinant CDK2/CyclinA2 est produite dans Baculovirus infected Insect Cells.

Aperçu rapide pour CDK2/CyclinA2 (Complex) Protéine (ABIN7938689)

Antigène: CDK2/CyclinA2

Type de proteíne: Recombinant

Origine: Humain

Source: Baculovirus infected Insect Cells

Application: Functional Studies (Func), Activity Assay (AcA), Screening Assay (ScA)

Détail du produit

Attributs du protein: Complex

Fonction: Recombinant CDK2 / Cyclin A2 Complex

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Recombinant CDK2 / Cyclin A2 Complex is supplied in 25 mM HEPES pH 7.5, 300 mM NaCl, 20 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Stock: -80 °C

Stockage commentaire: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Détail du antigène

Antigène: CDK2/CyclinA2

Autre désignation: CDK2 & Cyclin A2

Sujet:

Protein Background: CDK2 is a serine/threonine-protein kinase involved in the control of the cell cycle, essential for meiosis, but dispensable for mitosis. CDK2 / Cyclin A2 complex phosphorylate proteins like pocket proteins (Rb, p107, p130) and proteins involved in DNA synthesis, thereby driving S-phase progression. In line with its role in regulating S-phase and as a typical E2F target gene, cyclin A2 expression is induced upon entry into S-phase, persists through the S- and G2 phases, and is degraded upon entry into mitosis.

Short Description: Recombinant CDK2 / Cyclin A2 Complex that includes full length human CDK2 protein (accession number NP_001789.2) with an C-terminal His tag and full length human Cyclin A2 protein (accession number NP_001228.2) with an C-terminal FLAG tag was expressed in Hi5 cells. The molecular weights of CDK2 and Cyclin A2 are 35.57 kDa and 50.24 kDa, respectively.