CHD1L Protéine

N° du produit ABIN7938710

Protéine Recombinant CHD1L exprimée dans Baculovirus infected Insect Cells.

Aperçu rapide pour CHD1L Protéine (ABIN7938710)

Antigène: CHD1L (Chromodomain Helicase DNA Binding Protein 1-Like (CHD1L))

Type de proteíne: Recombinant

Origine: Humain

Source: Baculovirus infected Insect Cells

Application: Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)

Détail du produit

Fonction: Recombinant CHD1L protein

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Recombinant CHD1L protein is supplied in 25 mM HEPES pH 7.5, 300 mM NaCl, 20 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Stock: -80 °C

Stockage commentaire: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Détail du antigène

Antigène: CHD1L (Chromodomain Helicase DNA Binding Protein 1-Like (CHD1L))

Autre désignation: CHD1L

Sujet:

Protein Background: CHD1L is a ATP-dependent chromatin remodeler that mediates chromatin-remodeling following DNA damage. Recruited to DNA damage sites through interaction with poly-ADP-ribose: specifically recognizes and binds histones that are poly-ADP-ribosylated on serine residues in response to DNA damage. Poly-ADP-ribose-binding activates the ATP-dependent chromatin remodeler activity, thereby regulating chromatin during DNA repair. Catalyzes nucleosome sliding away from DNA breaks in an ATP dependent manner. Chromatin remodeling activity promotes PARP2 removal from chromatin.

Short Description: Recombinant CHD1L protein was expressed in a baculovirus expression system as the full-length protein (accession number NP_004275.4) with an N-terminal FLAG tag. The molecular weight of CHD1L is 102.27 kDa.

Aliases: ALC1, Amplified In Liver Cancer Protein 1, CHDL