CHD3 Protéine
Aperçu rapide pour CHD3 Protéine (ABIN7938711)
Antigène
Voir toutes CHD3 ProtéinesType de proteíne
Origine
Source
Application
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Fonction
- Recombinant CHD3 protein
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Recombinant CHD3 protein is supplied in 25 mM HEPES-NaOH pH 7.5, 300 mM NaCl, 10 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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Stock
- -80 °C
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Stockage commentaire
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))
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Autre désignation
- CHD3
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Sujet
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Protein Background: CHD3 (Chromodomain Helicase DNA Binding Protein 3) is a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/ NuRD complex which participates in the remodeling of chromatin by deacetylating histones and is required for anchoring centrosomal pericentrin in both interphase and mitosis, for spindle organization and centrosome integrity. Diseases associated with CHD3 include Snijders Blok-Campeau Syndrome and Agenesis Of Corpus Callosum, Cardiac, Ocular, And Genital Syndrome.
Short Description: Recombinant CHD3 protein was expressed in baculovirus expression system as the full length protein (accession number NP_005843.2) with a N-terminal FLAG tag. The molecular weight of the protein is 224 kDa.
Aliases: Chromodomain helicase DNA binding protein 3
Antigène
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