CHD6 Protein (AA 288-959)
Aperçu rapide pour CHD6 Protein (AA 288-959) (ABIN7938716)
Antigène
Type de proteíne
Origine
Source
Application
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Attributs du protein
- AA 288-959
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Fonction
- Recombinant CHD6 (288-959) protein
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Recombinant CHD6 (288-959) protein is supplied in 25 mM HEPES pH 7.5, 300 mM NaCl, 20 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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Stock
- -80 °C
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Stockage commentaire
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- CHD6 (Chromodomain Helicase DNA Binding Protein 6 (CHD6))
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Autre désignation
- CHD6
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Sujet
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Protein Background: CHD6 is a DNA-dependent ATPase that plays a role in chromatin remodeling. Regulates transcription by disrupting nucleosomes in a largely non-sliding manner which strongly increases the accessibility of chromatin. Activates transcription of specific genes in response to oxidative stress through interaction with NFE2L2. Activates transcription of specific genes in response to oxidative stress through interaction with NFE2L2.
Short Description: Recombinant CHD6 (288-959) protein that includes amino acids 288-959 of human CHD6 protein (accession number NP_115597.3) was expressed in a baculovirus expression system and contains an N-terminal FLAG Tag. The molecular weight of the protein is 79.55 kDa.
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Pathways
- Chromatin Binding
Antigène
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