DDX3X Protéine

N° du produit ABIN7938752

Cette protéine Recombinant DDX3X est produite dans Baculovirus infected Insect Cells.

Aperçu rapide pour DDX3X Protéine (ABIN7938752)

Antigène: DDX3X (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X))

Type de proteíne: Recombinant

Origine: Humain

Source: Baculovirus infected Insect Cells

Application: Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)

Détail du produit

Fonction: Recombinant DDX3X protein

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Recombinant DDX3X protein is supplied in 25 mM HEPES pH 7.5, 300 mM NaCl, 20 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Stock: -80 °C

Stockage commentaire: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Détail du antigène

Antigène: DDX3X (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X))

Autre désignation: DDX3X

Sujet:

Protein Background: DDX3X (ATP-dependent RNA helicase DDX3X) is a multifunctional ATP-dependent RNA helicase belonging to the DEAD-box protein family, which is critically involved in numerous aspects of RNA metabolism. Its primary function is to unwind RNA secondary structures, an essential activity that facilitates key processes including transcription, mRNA splicing, nuclear export, translation initiation, and the assembly of stress granules. Furthermore, DDX3X plays vital roles in innate immune signaling pathways by modulating the activity of key kinases and interferon responses. Due to its central role in gene expression and cell growth, mutations in the DDX3X gene are linked to neurodevelopmental disorders and various cancers, highlighting its importance in cellular homeostasis and disease.

Short Description: Recombinant DDX3X protein was expressed in a baculovirus expression system as the full length protein (accession number NP_001347.3) with an N-terminal FLAG tag. The molecular weight of DDX3X is 74.51 kDa.

Aliases: ATP-dependent RNA helicase DDX3X, DEAD-Box Helicase, DDX3X, DDX3, HLP2

Pathways: Ribonucleoprotein Complex Subunit Organization, Positive Regulation of Endopeptidase Activity, Negative Regulation of intrinsic apoptotic Signaling, Ribosome Assembly