EEF1A2 Protéine
Aperçu rapide pour EEF1A2 Protéine (ABIN7938818)
Antigène
Voir toutes EEF1A2 ProtéinesType de proteíne
Origine
Source
Application
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Fonction
- Recombinant EEF1A2 protein
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Attributs du produit
- EEF1A2 (Eukaryotic Translation Elongation Factor 1 Alpha 2), also called as EF1A or Statin, is an isoform of the alpha subunit of the elongation factor-1 complex. This complex is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. There are two isoforms for subunit alpha, EEF1A1 and EEF1A2. EEF1A2 promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. This isoform (alpha 2) is expressed in brain, heart and skeletal muscle, and the other isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas. This gene may be critical in the development of ovarian cancer.
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Recombinant EEF1A2 protein is supplied in 25 mM Tris-HCl pH 7.4, 500 mM NaCl, 10 % glycerol, and 0.5 mM TCEP.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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Stock
- -80 °C
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Stockage commentaire
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- EEF1A2 (Eukaryotic Translation Elongation Factor 1 alpha 2 (EEF1A2))
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Autre désignation
- EEF1A2
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Sujet
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Protein Background: EEF1A2 (Eukaryotic Translation Elongation Factor 1 Alpha 2), also called as EF1A or Statin, is an isoform of the alpha subunit of the elongation factor-1 complex. This complex is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. There are two isoforms for subunit alpha, EEF1A1 and EEF1A2. EEF1A2 promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. This isoform (alpha 2) is expressed in brain, heart and skeletal muscle, and the other isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas. This gene may be critical in the development of ovarian cancer.
Short Description: Recombinant EEF1A2 protein was expressed in E.coli as the full length protein (accession number NP_001949.1) with an N-terminal 6xHis Tag. The molecular weight of the protein is 54 kDa.
Aliases: Eukaryotic Translation Elongation Factor 1 Alpha 2
Antigène
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