PARG Protein (PARG) (AA 448-976)

N° du produit ABIN7939407

Cette protéine Recombinant PARG est exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour PARG Protein (PARG) (AA 448-976) (ABIN7939407)

Antigène: PARG

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Application: Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)

Détail du produit

Attributs du protein: AA 448-976

Fonction: Recombinant PARG (448-976) protein

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Recombinant PARG (448-976) protein is supplied in 25 mM Tris 8.0, 300 mM NaCl, 20 % glycerol, 0.5 mM TCEP.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Stock: -80 °C

Stockage commentaire: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Détail du antigène

Antigène: PARG

Autre désignation: PARG

Sujet:

Protein Background: PARG (Poly(ADP-ribose) glycohydrolase) catalyzes the hydrolysis of glycosidic bonds of ADP-ribose polymers, producing monomeric ADP-ribose units. Thus, in conjunction with poly(ADP-ribose) polymerase (PARP), PARG activity regulates the extent of in vivo poly(ADP ribosyl)ation. PARG acts both as an endo- and exoglycosidase, releasing poly(ADP-ribose) of different length as well as ADP-ribose monomers.Involved in the synthesis of ATP in the nucleus, together with PARP1, NMNAT1 and NUDT5.

Short Description: Recombinant PARG (448-976) protein that includes amino acids 448-976 of human PARG protein (accession number NP_003622.2) was expressed in E. coli cells with an C-terminal 6xHis tag. The molecular weight of the protein is 62.26 kDa.

Aliases: Poly(ADP-ribose) glycohydrolase, PARG, Mitochondrial Poly(ADP-Ribose) Glycohydrolase