SETD5 Protein (AA 185-416)
Aperçu rapide pour SETD5 Protein (AA 185-416) (ABIN7939563)
Antigène
Type de proteíne
Origine
Source
Application
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Attributs du protein
- AA 185-416
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Fonction
- Recombinant SETD5 (185-416) protein
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Indications d'application
- Recombinant SETD5 (185-416) protein is suitable for use in the study of enzyme kinetics, inhibitor screening, and selectivity profiling.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Recombinant SETD5 (185-416) protein is supplied in 25 mM Tris-HCl pH 7.4, 500 mM NaCl, 10 % glycerol and 0.5 mM TCEP.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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Stock
- -80 °C
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Stockage commentaire
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- SETD5 (SET Domain Containing 5 (SETD5))
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Autre désignation
- SETD5
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Sujet
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Protein Background: SETD5 (SET Domain Containing 5), based on sequence similarity, is a member of SET domain proteins, and might displays histone methyltransferase activity in vitro. It was reported to monomethylate 'Lys-9' of histone H3 in vitro. The physiological significance of this activity is unclear and its activity has yet to be determined. SETD5 is a probable transcriptional regulator that acts via the formation of large multiprotein complexes that modify and/or remodel the chromatin. According to researchers, it may act as a regulator of histone acetylation during gene transcription.
Short Description: Recombinant SETD5 (185-416) protein that includes amino acids 185-416 of human SETD5 protein (accession number NP_001073986.1) was expressed in E.coli and contains an N-terminal 6xHis tag. The molecular weight of this SETD5 protein is 30.4 kDa.
Aliases: SET Domain Containing 5, Histone-Lysine N-Methyltransferase SETD5, EC 2.1.1.43
Antigène
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