YTHDC2 Protein (full length)

N° du produit ABIN7939765

Protéine Recombinant YTHDC2 exprimée dans Baculovirus infected Insect Cells.

Aperçu rapide pour YTHDC2 Protein (full length) (ABIN7939765)

Antigène: YTHDC2 (YTH Domain Containing 2 (YTHDC2))

Type de proteíne: Recombinant

Origine: Humain

Source: Baculovirus infected Insect Cells

Application: Screening Assay (ScA), Activity Assay (AcA), Functional Studies (Func)

Détail du produit

Attributs du protein: full length

Fonction: Recombinant YTHDC2 protein

Attributs du produit: Recombinant YTHDC2 protein was expressed in a baculovirus expression system as the full-length protein (accession number NP_073739.3) with an N-terminal Flag tag. The molecular weight of the protein is 161.5 kDa. It is suitable for use in binding assays, inhibitor screening, and selectivity profiling.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Recombinant YTHDC2 protein is supplied in 25 mM HEPES-NaOH pH 7.5, 300 mM NaCl, 10 % glycerol, 0.04 % Triton X-100, and 0.5 mM TCEP.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Stock: -80 °C

Stockage commentaire: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Détail du antigène

Antigène: YTHDC2 (YTH Domain Containing 2 (YTHDC2))

Autre désignation: YTHDC2

Sujet:

Protein Background: YTHDC2 (YTH Domain Containing 2), is a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. It specifically recognizes and binds to N6-methyladenosine (m6A), a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. YTHDC2 may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line.

Short Description: Recombinant YTHDC2 protein was expressed in a baculovirus expression system as the full length protein (accession number NP_073739.3) with an N-terminal Flag tag. The molecular weight of the protein is 161.5 kDa.

Aliases: YTH Domain Containing 2

Poids moléculaire: 161.5 kDa

NCBI Accession: NP_073739