Stabilized Troponin I Protéine

N° du produit ABIN934429

Protéine Recombinant exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour Stabilized Troponin I Protéine (ABIN934429)

Antigène: Stabilized Troponin I

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Détail du produit

Attributs du produit: Purified recombinant Human Stabilized Troponin I protein (Cardiac)
Expression System: E.coli

Information d'application

Indications d'application: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Stockage

Concentration: 10-50 µg/mL

Buffer: Supplied in 500 mM NaCl, 5 mM sodium phosphate, 2 mM CaCl2, 0.5 mM EDTA, 0.025 % Sodium Azide, pH 7.5.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -25 °C or below.

Détail du antigène

Antigène: Stabilized Troponin I

Sujet: Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle.
Alternative Names: Cardiac-specific troponin I protein, cTnl protein, TnI protein, Troponin I protein