HIV-1 Transmembrane Glycoprotein (HIV-1 gp41) (AA 546-682), (Ecto Domain) Protéine

N° du produit ABIN934613

Cette protéine Recombinant est produite dans Levure. Il y a 2 publications disponibles.

Aperçu rapide pour HIV-1 Transmembrane Glycoprotein (HIV-1 gp41) (AA 546-682), (Ecto Domain) Protéine (ABIN934613)

Antigène: HIV-1 Transmembrane Glycoprotein (HIV-1 gp41)

Type de proteíne: Recombinant

Origine: Human Immunodeficiency Virus (HIV)

Source: Levure

Application: ELISA, Western Blotting (WB)

Pureté: > 99 % pure

Détail du produit

Attributs du protein: Ecto Domain, AA 546-682

Attributs du produit: Purified recombinant HIV1 gp41 protein
Expression System: Yeast
This protein comprises of Ecto-domain of gp41 from Strain HxB2, amino acids 546 to 682

Information d'application

Indications d'application: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied as a liquid in 20 mM Sodium Phosphate buffer, 500 mM NaCl, 0.2 % Triton X-100, and 6 M Urea, pH 7.4.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -80 °C

Stockage commentaire: Aliquot and store at -70 °C or lower.

Référence

Du, Idiart, Mariano, Chen, Jiang, Xu, Ostrow, Wrin, Phung, Binley, Petropoulos, Ballantyne, Whalen: "Effect of trimerization motifs on quaternary structure, antigenicity, and immunogenicity of a noncleavable HIV-1 gp140 envelope glycoprotein." dans: Virology, Vol. 395, Issue 1, pp. 33-44, (2009) (PubMed).

Opalka, Pessi, Bianchi, Ciliberto, Schleif, McElhaugh, Danzeisen, Geleziunas, Miller, Eckert, Bramhill, Joyce, Cook, Magilton, Shiver, Emini, Esser: "Analysis of the HIV-1 gp41 specific immune response using a multiplexed antibody detection assay." dans: Journal of immunological methods, Vol. 287, Issue 1-2, pp. 49-65, (2004) (PubMed).

Détail du antigène

Antigène: HIV-1 Transmembrane Glycoprotein (HIV-1 gp41)

Autre désignation: HIV1 gp41

Classe de substances: Viral Protein

Sujet: HIV gp41 is a glycoprotein subunit that remains non-covalently-bound to gp120, and provides the second step by which HIV enters the cell. It is originally buried within the viral envelope, but, when gp120 binds to a CD4, gp120 changes its conformation, causing gp41 to become exposed, where it can assist in fusion with the host cell. The Env gene does not, in fact, code for gp120 and gp41, but for a precursor to both, gp160. During HIV reproduction, the host cell's own enzymes cleave gp160 into gp120 and gp41.
Alternative Names: HIV-1 gp41 protein, SU antigen, Surface protein antigen, HIV1 gp41, Envelope surface glycoprotein gp41 antigen, HIV-1 gp41, Human Immunodeficiency Virus 1 antigen, gp41 antigen, HIV 1 gp41, HIV 1 gp41 protein, gp41 glycoprotein antigen, gp41 antigen, Glycoprotein 41 antigen, HIV 1 gp41 antigen, HIV-1 gp41 antigen