Troponin I Protein (TNNI)

N° du produit ABIN934718

Cette protéine Native Troponin I est produite dans Human. Il y a 1 publication disponible.

Aperçu rapide pour Troponin I Protein (TNNI) (ABIN934718)

Antigène: Troponin I (TNNI)

Type de proteíne: Native

Origine: Humain

Source: Human

Pureté: > 99 % pure

Détail du produit

Attributs du produit: Purified native Human Troponin I protein (Cardiac)
Protein Source: Human cardiac tissue

Information d'application

Indications d'application: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied as a liquid in 8 M Urea buffer with 30 mM NaCl, 50 mM Tris. HCl, 15 mM beta-mercaptoethanol, 1 mM EGTA, pH 8.0

Précaution d'utilisation: Donor samples were tested and found to be negative for HBsAg, Anti-HIV-1/HIV-2, & HCV. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -20 °C/-80 °C

Stockage commentaire: Store at -20 °C to -70 °C,

Référence

Mulvaney, Cole, Kniller, Malito, Tamanaha, Rife, Stanton, Whitman: "Rapid, femtomolar bioassays in complex matrices combining microfluidics and magnetoelectronics." dans: Biosensors & bioelectronics, Vol. 23, Issue 2, pp. 191-200, (2007) (PubMed).

Détail du antigène

Antigène: Troponin I (TNNI)

Autre désignation: Troponin I

Sujet: Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle. The letter I is given due to its inhibitory character.
Description: Human cardiac tissue.