Troponin C Protéine

N° du produit ABIN934719

Détail du produit

Antigène: Troponin C

Type de proteíne: Native

Origine: Humain

Source: Human

Attributs du produit: Purified native Human Troponin C protein (Cardiac)
Protein Source: Human cardiac tissue

Pureté: > 95 % pure

Information d'application

Indications d'application: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Stockage

Buffer: 10 mM Na0 O4, pH 7.2, with 150 M NaCl, and 0.05 % NaN3.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -20 °C

Stockage commentaire: Ships on dry ice. Upon receipt store at or below -25 °C

Référence

Song, Han, Kim, Yang, Yoon: "A fluoro-microbead guiding chip for simple and quantifiable immunoassay of cardiac troponin I (cTnI)." dans: Biosensors & bioelectronics, Vol. 26, Issue 9, pp. 3818-24, (2014) (PubMed).

Détail du antigène

Antigène: Troponin C

Sujet: Troponin C is a part of the troponin complex. It contains four calcium-binding EF hands. It is a component of thin filaments (along with actin and tropomyosin). It contains an N lobe and a C lobe. The C lobe serves a structural purpose and binds to the N domain of TnI. The C lobe can bind either Ca2+ or Mg2+. The N lobe, which binds only Ca2+, is the regulatory lobe and binds to the C domain of TnI after calcium binding.
Description: Human cardiac tissue.