Factor VII Protéine

N° du produit ABIN934812

Cette protéine Native Factor VII est exprimée dans Human.

Aperçu rapide pour Factor VII Protéine (ABIN934812)

Antigène: Factor VII (F7) (Coagulation Factor VII (F7))

Type de proteíne: Native

Activité biologique: Active

Origine: Humain

Source: Human

Pureté: > 95 % pure

Détail du produit

Attributs du produit: Purified native Human Factor VII protein
Bioactivity: 3296 units/mg protein - Specific activity is determined by the Factor VII clotting assay. One unit of activity is equivalent to the factor VII activity in one milliliter of normal plasma.
Protein Source: Human serum/plasma

Information d'application

Indications d'application: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Stockage

Buffer: 50 % Glycerol/H2 O (vol/vol).

Précaution d'utilisation: Donor samples were tested and found to be negative for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -20 °C

Stockage commentaire: Aliquot and store at -20 °C.

Détail du antigène

Antigène: Factor VII (F7) (Coagulation Factor VII (F7))

Autre désignation: Factor VII

Sujet: Human factor VII is a single chain, vitamin K-dependent, plasma glycoprotein which is synthesized in the liver. Prior to secretion into the blood, post translational modification by a vitamin K-dependent carboxylase produces ten-carboxyglutamic acid (gla) residues located in the NH2-terminal portion of the molecule, which facilitate cell membrane binding. Factor VII is proteolytically activated to the serine protease, factor VIIa, during coagulation. Factor VII can be activated by thrombin, factor IXa, factor Xa or factor XIIa.
Description: Human serum/plasma.
Alternative Names: Complement Factor VII

Poids moléculaire: 50 kDa

Pathways: Response to Growth Hormone Stimulus, Platelet-derived growth Factor Receptor Signaling