G-CSF Protéine
Aperçu rapide pour G-CSF Protéine (ABIN934916)
Antigène
Voir toutes G-CSF (CSF3) ProtéinesType de proteíne
Activité biologique
Origine
Source
Application
Pureté
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Séquence
- MTPLGPASSL PQSFLLKCLE QVRKIQGDGA ALQEKLCATY KLCHPEELVL LGHSLGIPWA PLSSCPSQAL QLAGCLSQLH SGLFLYQGLL QALEGISPEL GPTLDTLQLD VADFATTIWQ QMEELGMAPA LQPTQGAMPA FASAFQRRAG GVLVASHLQS FLEVSYRVLR HLAQP
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Attributs du produit
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Purified recombinant Human GCSF protein
Expression System: E.coli
Bioactivity: The proliferative activity of rhG-CSF is tested in culture using murine bone marrow cells.
Molecular weight on SDS-PAGE will appear higher.
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Indications d'application
- GCSF protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Supplied as a liquid in PBS, pH 7.4.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- RT/-20 °C
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Stockage commentaire
- Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
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- G-CSF (CSF3) (Colony Stimulating Factor 3 (Granulocyte) (CSF3))
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Autre désignation
- GCSF
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Sujet
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Human granulocyte colony-stimulating factor (hG-CSF) is one of the hematopoietic growth factors which plays an important role in stimulating proliferation, differentiation, and functional activation of blood cells. In addition to its effect on hematopoiesis, G-CSF also enhances neutrophil functions against bacteria, fungi, and tumor cells mediated by antibody-dependent cell-mediated cytotoxicity. Recombinant hG-CSF was expressed in E. coli and purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
Alternative Names: CSF3 protein, Csfg protein, CSF beta protein, Granulocyte-colony stimulating factor Colony stimulating factor 3 (granulocyte) protein, MGC45931 protein, CSF 3 protein, , Granulocyte colony stimulating factor protein, Lenograstim protein, Filgrastim protein, Pluripoietin protein, GCSA protein, GCSF protein, Lenograstim protein, Macrophage granulocyte inducer 2 protein, G-CSF protein, G-CSF protein, MGI 2 protein, Granulocyte colony-stimulating factor protein -
Poids moléculaire
- 18.8 kDa (175 AA)
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization
Antigène
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