Translin Protein (TSN) (AA 1-228)
Aperçu rapide pour Translin Protein (TSN) (AA 1-228) (ABIN935103)
Antigène
Voir toutes Translin (TSN) ProtéinesType de proteíne
Origine
Source
Application
Pureté
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Attributs du protein
- AA 1-228
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Séquence
- MSVSEIFVEL QGFLAAEQDI REEIRKVVQS LEQTAREILT LLQGVHQGAG FQDIPKRCLK AREHFGTVKT HLTSLKTKFP AEQYYRFHEH WRFVLQRLVF LAAFVVYLET ETLVTREAVT EILGIEPDRE KGFHLDVEDY LSGVLILASE LSRLSVNSVT AGDYSRPLHI STFINELDSG FRLLNLKNDS LRKRYDGLKY DVKKVEEVVY DLSIRGFNKE TAAACVEK
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Attributs du produit
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Purified recombinant Human TSN protein
Expression System: E.coli
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Indications d'application
- TSN protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Supplied as a liquid in 20 mM Tris-HCl buffer, pH 8.0, containing 0 mM DTT, 10 % glycerol and 100 mM NaCl.
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Agent conservateur
- Dithiothreitol (DTT)
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Précaution d'utilisation
- This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- RT/-20 °C
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Stockage commentaire
- Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
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- Translin (TSN)
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Autre désignation
- TSN
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Sujet
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Translin, also known as TSN, is a DNA and RNA binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin forms a ring-shaped structure, which is responsible for DNA binding, and also contains a leucine zipper motif, which is thought to enable translin to form dimers. Translin exports specific mRNAs out of the nucleus, supported by its localization in both the nuclei and cytoplasm of neurons, and regulates their translation. Recombinant human Translin protein, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: BCLF-1 protein, REHF-1 protein, RCHF1 protein, Translin protein, TBRBP protein, TRSLN -
Poids moléculaire
- 26.1 kDa (228 AA)
Antigène
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