Nanog Protein (AA 1-305)

N° du produit ABIN935111

Cette protéine Recombinant Nanog est produite dans Escherichia coli (E. coli).

Aperçu rapide pour Nanog Protein (AA 1-305) (ABIN935111)

Antigène: Nanog (NANOG) (Nanog Homeobox (NANOG))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Pureté: > 90 % pure

Détail du produit

Attributs du protein: AA 1-305

Séquence: MSVDPACPQS LPCFEASDCK ESSPMPVICG PEENYPSLQM SSAEMPHTET VSPLPSSMDL LIQDSPDSST SPKGKQPTSA EKSVAKKEDK VPVKKQKTRT VFSSTQLCVL NDRFQRQKYL SLQQMQELSN ILNLSYKQVK TWFQNQRMKS KRWQKNNWPK NSNGVTQKAS APTYPSLYSS YHQGCLVNPT GNLPMWSNQT WNNSTWSNQT QNIQSWSNHS WNTQTWCTQS WNNQAWNSPF YNCGEESLQS CMQFQPNSPA SDLEAALEAA GEGLNVIQQT TRYFSTPQTM DLFLNYSMNM QPEDV

Attributs du produit: Purified recombinant Nanog protein
Expression System: E.coli

Information d'application

Indications d'application: Nanog protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Supplied as a liquid in 20 mM Tris-HCl buffer, pH 8.0, containing 0.4 M Urea and 5 % glycerol.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: RT/-20 °C

Stockage commentaire: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Détail du antigène

Antigène: Nanog (NANOG) (Nanog Homeobox (NANOG))

Autre désignation: Nanog

Sujet: Nanog homeobox, also known as nanog, is a member of the homeobox family of DNA binding transcription factors that has been shown to maintain pluripotency of embryonic stem cells. Nanog expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF, Stat3 and BMP. Once NANOG expression is downregulated, cell differentiation can proceed. Proteins which regulate NANOG expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53.
Alternative Names: Homeobox transcription factor Nanog protein, homeobox transcription factor Nanog-delta 48 protein

Poids moléculaire: 34.6 kDa (305 AA)

Pathways: Stem Cell Maintenance