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Globular Acrp30 (Adipolean) (Active) Protéine

Protéine Recombinant exprimée dans Escherichia coli (E. coli).
N° du produit ABIN935218

Aperçu rapide pour Globular Acrp30 (Adipolean) (Active) Protéine (ABIN935218)

Antigène

Globular Acrp30 (Adipolean)

Type de proteíne

Recombinant

Activité biologique

Active

Origine

  • 1
  • 1
Humain

Source

  • 2
Escherichia coli (E. coli)

Pureté

> 98 % pure
  • Séquence

    PGAEGPRGFP GIQGRKGEPG EGAYVYRSAF SVGLETYVTI PNMPIRFTKI FYNQQNHYDG STGKFHCNIP GLYYFAYHIT VYMKDVKVSL FKKDKAMLFT YDQYQENNVD QASGSVLLHL EVGDQVWLQV YGEGERNGLY ADNDNDSTFT GFLLYHDTN

    Attributs du produit

    Purified recombinant Human gAcrp30 protein
    Expression System: E.coli
    Bioactivity: Determined by a cytotoxicity assay using M1 cells. The expected ED50 for this effect is 0.5-1.0 µg/mL.

    niveau d'endotoxine

    < 0.1 ng per µg (1 EU/µg).
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  • Indications d'application

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Supplied as a lyophilized powder.

    Conseil sur la manipulation

    Avoid repeated freeze/thaw cycles.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • Antigène

    Globular Acrp30 (Adipolean)

    Sujet

    The gAcrp30 variant is a naturally occurring globular protein, obtained by proteolytic processing of adiponectin. Adiponectin is produced and secreted exclusively by adipocytes, and is a relatively abundant plasma protein, accounting for up to 0.05 % of total serum protein. Like Adiponectin, Acrp30 is capable of decreasing hyperglycemia and reversing insulin resistance. Additionally, gAcrp30 has been shown to be an important factor in promoting fat loss by signaling muscle to absorb and burn Free-Fatty Acids (FFAs). The signaling receptors for adiponectin and gAcrp30 have recently been identified and names AdipoR1 and AdipoR2. AdipoR2 is predominantly expressed in the liver.
    Alternative Names: Adiponectin protein, gAcrp 30, gAcrp-30 protein, gAcrp-30 protein, gAcrp-30, apm-1 variant protein, gAcrp 30 protein, gAcrp30

    Poids moléculaire

    18.1 kDa
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